Nerve fiber growth in culture on fibronectin, collagen, and glycosaminoglycan substrates
نویسندگان
چکیده
منابع مشابه
Nerve fiber growth in culture on fibronectin, collagen, and glycosaminoglycan substrates.
In an initial report (Carbonetto, S. T., M. M. Gruver, and D. C. Turner (1982) Science 216: 897-899) we described the use of 2-hydroxyethylmethacrylate (HEMA) in preparing defined culture substrates for studying nerve fiber growth. In those studies fibronectin and collagen were conspicuous, among a variety of HEMA-embedded proteins, in supporting fiber growth of embryonic neurons from chick dor...
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In adult mammals, injured neurons regenerate extensively within the PNS but poorly, if at all, within the CNS. We have studied the effect of substrata consisting of tissue sections from various nervous systems on nerve fiber growth in culture and correlated our results with the growth potential of these tissues in vivo. Ganglionic explants from embryonic chicks (9-12 d) fail to extend nerve fib...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1983
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.03-11-02324.1983